Just days before the deadline to turn in signatures, a Cole County judge hears arguments over whether 92,000 signatures ...

PEACH ORCHARD, Mo. (KFVS) - President Donald Trump says money is on the way to U.S. farmers, hurt by the trade war with China ...

SOUTHEAST MISSOURI (KFVS) - A Heartland holiday tradition is marking two decades. The Christmas Country Church Tour will take ...

(Gray News) - The Powerball jackpot reached $875 million before Monday night’s drawing. If won, it would be the seventh ...

An East Prairie man was seriously injured in a single-vehicle crash in Mississippi County on Monday, December 8.

According to the Missouri State Highway Patrol, there is a multi-vehicle crash on Nash Road/MO-AB south of County Road 217.

PADUCAH, Ky. (KFVS) - Two Metropolis women and a Paducah man were arrested in connection with a robbery investigation. Quante ...

HARRISBURG, Ill. (KFVS) - A nonprofit program in southern Illinois will host two free community events to celebrate Christmas ...

The ISA is now planning to partner with the Franklin County Sheriff’s Office in a pilot program that involves a partnership ...

In Williamson County, Southern Illinois Healthcare is expanding access to advanced cancer clinical trials, including a global ...

Poplar Bluff City Manager Robert Knodell now admits to driving after drinking alcohol back in October and announces he is ...

Chris Wuestling told First Alert 4 he was about to catch his bus to head to work Friday afternoon when he watched a Granite ...